EXACT Sciences (EXAS) had the highest return between November 10, 2005 and January 15, 2006 by a large-cap US stock, returning 132%.

Insmed (INSM) had the highest return between November 10, 2005 and January 3, 2006 by a large-cap US stock, returning 85.2%.

Insmed (INSM) had the highest return between November 1, 2005 and January 3, 2006 by a large-cap US stock, returning 76%.

Insmed (INSM) had the highest return between November 15, 2005 and January 3, 2006 by a large-cap US stock, returning 80.5%.

Microsoft (MSFT) returned 89.4% in 1986.

Monolithic Power Systems (MPWR) had the highest return between September 10, 2005 and November 15, 2005 by a large-cap US stock, returning 110.5%.

Sarepta Therapeutics (SRPT) had the highest return between September 10, 2005 and November 1, 2005 by a large-cap US stock, returning 58%.

The closing price for Microsoft (MSFT) in 1990 was $0.64, on December 31, 1990. It was up 72.5% for the year. The latest price is $435.27.

Sorry, I don't have the answer to that one.

Insmed (INSM) had the highest return between November 10, 2005 and December 30, 2005 by a large-cap US stock, returning 71.3%.

Banco Bradesco SA ADR (BBD) had the highest return between September 10, 2005 and November 10, 2005 by a large-cap US stock, returning 83.5%.

Monolithic Power Systems (MPWR) had the highest return between September 10, 2005 and October 30, 2005 by a large-cap US stock, returning 58.8%.

Regeneron Pharmaceuticals (REGN) had the highest return between September 1, 2005 and October 30, 2005 by a large-cap US stock, returning 60%.

Banco Bradesco SA ADR (BBD) had the highest return between September 1, 2005 and November 30, 2005 by a large-cap US stock, returning 114.8%.

PCB Bancorp (PCB) had the highest return between 2005 and 2015 by a US stock, returning 11,924,221,883.8%.