Americas Car-Mart (CRMT) had the highest return in 1993 by a US stock, returning 1,242.7%.

Lisata Therapeutics (LSTA) had the highest return in 1994 by a US stock, returning 4,285,614.3%.

Lisata Therapeutics (LSTA) had the highest return between 1994 and 1997 by a US stock, returning 1,178,471.4%.

QQQ has had its best month this year this month, returning 8.2%.

Portage Biotech (PRTG) had the highest return between 1995 and 1997 by a US stock, returning 111,900%.

Madrigal Pharmaceuticals (MDGL) had the highest return between November 1, 2022 and December 31, 2022 by a mid-cap US stock or mid-cap US stock, returning 301.6%.

INVO Bioscience (INVO) returned -85% last year.

INVO Bioscience (INVO) returned -58.4% in 2019.

INVO Bioscience (INVO) returned 169.2% in 2018.

INVO Bioscience (INVO) returned -55.7% in 2017.

INVO Bioscience (INVO) returned 914.5% in 2016.

INVO Bioscience (INVO) returned -86.5% in 2015.

INVO Bioscience (INVO) returned 381.5% in 2014.

INVO Bioscience (INVO) returned 260% in 2013.

INVO Bioscience (INVO) returned -45.5% in 2012.