Regeneron Pharmaceuticals (REGN) had the highest return in 2012 by a US stock in the S&P 500 (GSPC), returning 202.7%.

Sorry, available market cap data for Alphabet Inc Class A (GOOGL) starts on August 19, 2004. Alphabet Inc Class A (GOOGL) has a market capitalization of $2.2T, based on 12.17B shares at a price of $179.63 (up 1.5% yesterday).

On December 31, 2004, Alphabet Inc Class A (GOOGL) had a market capitalization of $52.6B, based on 10.93B shares at a price of $4.81.

The closing price for Bitcoin (BTC) on February 12, 2022 was $42,241.00. It was down 0.4% for the day. The latest price is $66,530.

The closing price for Bitcoin (BTC) in May 2013 was $129, on May 31, 2013. It was down 7.2% for the month. The latest price is $66,006.60.

The closing price for Bitcoin (BTC) on February 5, 2022 was $41,427.52. It was down 0.2% for the day. The latest price is $59,236.

The closing price for NVIDIA (NVDA) between 2020 and 2022 was $14.60, on December 30, 2022. It was up 145.7% in that time. The latest price is $138.

The closing price for Bitcoin (BTC) on May 8, 2022 was $34,026.74. It was down 4.1% for the day. The latest price is $66,530.

The closing price for NVIDIA (NVDA) between 2021 and 2022 was $14.60, on December 30, 2022. It was up 11.7% in that time. The latest price is $138.

Sorry, I couldn't find pricing data for that day. The closing price for silver (XAG) on February 6 was $22.30.

The closing price for Costco Wholesale (COST) in October 2022 was $484.48, on October 31, 2022. It was up 5.9% for the month. The latest price is $893.58.

The closing price for Costco Wholesale (COST) in 2022 was $441.64, on December 30, 2022. It was down 18.7% for the year. The latest price is $809.73.

Summit Therapeutics (SMMT) had the highest return between April 1, 2024 and August 31, 2024 by a large-cap US stock, returning 208.3%.

The closing price for Costco Wholesale (COST) in October 2020 was $332.37, on October 30, 2020. It was up 0.6% for the month. The latest price is $809.73.

The closing price for Costco Wholesale (COST) in October 2023 was $537.51, on October 31. It was down 2.7% for the month. The latest price is $809.73.