Doug Martin earned the most fantasy points in a game in 2012, with 51.2 points versus the Oakland Raiders on November 4, 2012.

Jamaal Charles earned the most fantasy points in a game in 2013, with 51.5 points against the Oakland Raiders on December 15, 2013.

Ben Roethlisberger racked up the most fantasy points in a game in 2014, with 44.8 points against the Colts on October 26, 2014.

Le'Veon Bell collected the most fantasy points in a game in 2016, with 47.8 points against the Bills on December 11, 2016.

Drew Brees racked up the most fantasy points in a game in 2015, with 46.3 points against the Giants on November 1, 2015.

Breece Hall is currently RB5 with 183.3 fantasy points on the year, and he had 31.1 fantasy points against the Colts in Week 11, rushing for 78 yards and 1 touchdown and adding 43 receiving yards for 1 touchdown. He has his bye week this week.

Todd Gurley racked up the most fantasy points in a game in 2017, with 42 points versus the Seahawks on December 17, 2017.

Joe Mixon is one of only 3 running backs with four 100-yard rushing games, along with Derrick Henry and Saquon Barkley. He had 23.4 fantasy points against the Colts in Week 8, rushing for 102 yards and 1 touchdown. He is projected to put up 18.4 fantasy points against the Jets which makes him RB6 this week.

Derrick Henry had the most fantasy points in a game in 2018, with 47.8 points versus the Jaguars on December 6, 2018.

Aaron Rodgers collected the most fantasy points in a game in 2019, with 43.8 points against the Oakland Raiders on October 20, 2019.

Ja'Marr Chase has the most fantasy points by a wide receiver this season, with 178.7 points.

Alvin Kamara collected the most fantasy points in a game in 2020, with 53.2 points versus the Vikings on December 25, 2020.

Jonathan Taylor had the most fantasy points in a game in 2021, with 50.4 points versus the Bills on November 21, 2021.

Joe Mixon collected the most fantasy points in a game in 2022, with 51.1 points against the Panthers on November 6, 2022.

De'Von Achane had the most fantasy points in a game in 2023, with 47.3 points versus the Broncos on September 24, 2023.