The Indianapolis Colts lost to the Pittsburgh Steelers, 21 to 18, in the 2005 AFC divisional game on January 15, 2006.

The Indianapolis Colts lost to the Pittsburgh Steelers, 21 to 18, in the 2005 AFC divisional game on January 15, 2006.
1st quarter
PIT
IND
Antwaan Randle El 6-yard pass from Ben Roethlisberger (Jeff Reed kick)
7
0
Heath Miller 7-yard pass from Ben Roethlisberger (Jeff Reed kick)
14
0
2nd quarter
PIT
IND
Mike Vanderjagt 20-yard field goal
14
3
3rd quarter
PIT
IND
Jerome Bettis 1-yard run (Jeff Reed kick)
21
3
4th quarter
PIT
IND
Dallas Clark 50-yard pass from Peyton Manning (Mike Vanderjagt kick)
21
10
Edgerrin James 3-yard run (Peyton Manning pass to Reggie Wayne for two-point conversion)
21
18