IQIYI (IQ) had the highest return between November 1, 2022 and December 31, 2022 by a mid-cap US stock, returning 138.7%.

Applied Digital (APLD) had the lowest return in June 2022 by a mid-cap US stock or mid-cap US stock, returning -78.8%.

Applied Digital (APLD) had the lowest return in June 2022 by a mid-cap US stock or mid-cap US stock, returning -78.8%.

The closing price for Coinbase Global (COIN) between April 1, 2024 and October 31, 2024 was $179.25, on October 31, 2024. It was down 31.6% in that time. The latest price is $274.19.

ZTST (ZTST) has had the highest return since January 1, 2025 by a US stock, returning 30,631.9%.

The closing price for Bitcoin (BTC) between April 1, 2024 and October 31, 2024 was $70,215.19, on October 31, 2024. It was down 1.6% in that time. The latest price is $90,257.98.

The closing price for Bitcoin (BTC) in 2018 was $3,742.70, on December 31, 2018. It was down 73.5% for the year. The latest price is $90,852.56.

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Trump Media & Technology (DJT) had the highest return between December 1, 2021 and January 31, 2022 by a mid-cap US stock, returning 76.2%.

Alpha Metallurgical Resources (AMR) had the highest return between December 1, 2021 and January 31, 2024 by a mid-cap US stock, returning 780.4%.

Hagerty (HGTY) had the highest return in December 2021 by a mid-cap US stock, returning 38.9%.

NVIDIA (NVDA) had its best year between January 1, 2023 and December 31, 2023 last year, returning 233.6%.

Aimei Health Technology Co, Ltd Ordinary Share (AFJK) has had the highest return today by a US stock, returning 814.3%.

Lantheus (LNTH) had the highest return between November 1, 2021 and August 31, 2022 by a mid-cap US stock, returning 237.2%.

Sorry, I don't have the answer to that one.