Tectonic Therapeutic (TECX) has had the highest return since January 1, 2024 by a US stock, returning 5,407,400%.

Connexa Sports Technologies (YYAI) had the highest return in 2020 by a US stock, returning 7,199,900%.

Exelixis (EXEL) had the highest return between January 1, 2015 and June 30, 2018 by a large-cap US stock, returning 1,363.9%.

Tesla (TSLA) had the highest return between 2013 and 2014 by a US stock in the S&P 500 (GSPC), returning 535.5%.

Blackboxstocks (BLBX) had the highest return between January 1, 2015 and June 30, 2018 by a US stock, returning 2,752,841.2%.

NVIDIA (NVDA) had the highest return between 2013 and 2017 by a US stock in the S&P 500 (GSPC), returning 1,551.4%.

Tesla (TSLA) had its best year since June 29, 2010 in 2020, returning 731.2%.

American Express (AXP) returned 602.6% between 1990 and 1999.

American Express (AXP) returned 770.9% between 1993 and 1999.

American Express (AXP) returned 104.9% between 1993 and 1995.

American Express (AXP) returned 25.4% in 1992.

American Express (AXP) returned 5.4% in 1991.

American Express (AXP) returned -38.1% in 1990.

Sorry, I couldn't find pricing data for that day. The closing price for MSCI (MSCI) on December 30, 2022 was $456.16. It was down 0.3% for the day. The latest price is $605.99.

Sorry, I couldn't find pricing data for that day. The closing price for MSCI (MSCI) on December 29 was $560.63. It was down 0.7% for the day. The latest price is $605.99.