The Nasdaq Composite (IXIC) has had the highest return since March 12, 1990 by a major index, returning 5,083.6%.

Aurora Cannabis (ACB) had the highest return between January 1, 2009 and December 31, 2018 by a US stock, returning 7,935,900%.

InterContinental Hotels Group PLC ADR (IHG) had the highest return between January 1, 2000 and December 31, 2008 by a US stock, returning 5,519,600%.

InterContinental Hotels Group PLC ADR (IHG) had the highest return between January 1, 2000 and December 31, 2009 by a US stock, returning 9,928,700%.

The average closing price for Bitcoin (BTC) in 2021 was $47,436.93. It was up 59.7% for the year. The latest price is $89,516.91.

The closing price for Tesla (TSLA) in 2017 was $20.76, on December 29, 2017. It was up 44.9% for the year. The latest price is $403.98.

InterContinental Hotels Group PLC ADR (IHG) had the highest return between January 1, 2000 and January 1, 2005 by a US stock, returning 8,020,800%.

Astrana Health (ASTH) had the highest return between January 1, 2005 and December 1, 2021 by a US stock, returning 8,537,900%.

Astrana Health (ASTH) had the highest return between January 1, 2005 and December 1, 2020 by a US stock, returning 1,802,900%.

Cemtrex (CETX) had the highest return between January 1, 2005 and January 1, 2010 by a US stock, returning 22,635,714.9%.

Hirequest (HQI) had the highest return between January 1, 1990 and January 1, 2006 by a US stock, returning 43,752,250%.

Hirequest (HQI) had the highest return between January 1, 2000 and January 1, 2006 by a US stock, returning 43,752,250%.

Sitio Royalties (STR) had the highest return between May 20, 2004 and May 20, 2019 by a US stock, returning 18,732,600%.

Cemtrex (CETX) had the highest return between May 20, 2004 and May 20, 2010 by a US stock, returning 453,172,105.4%.

Cemtrex (CETX) had the highest return between May 20, 2004 and May 20, 2015 by a US stock, returning 453,172,105.4%.