Since 2021-22, 6 players are tied for the lowest plus/minus in a game, at -6. The first three are Jamie Drysdale on April 9, Henry Thrun on March 19 and Anze Kopitar on February 13.

which player had worst plus minus in one game since 2022
Interpreted as:
Which player had worst plus minus in one regular-season game since 2022?

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