Since 1999-00, 6 players are tied for the most goals in a game, with 5 scored. The first three are Tage Thompson on December 7, 2022, Timo Meier on January 17, 2022 and Mika Zibanejad on March 5, 2020.

most goals scored by a single player in an nhl game since 2000
Interpreted as:
most goals scored by a single player in an NHL regular-season game since 2000

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