| NAME | RUSH YDS | SEASON | TM | GP | ATT | YPC | RUSH YDS/G | RUSH TD | REC YDS | REC | TRG | AVG | REC YDS/G | REC TD | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Arian Foster | 1,616 | 2010 |  HOU | 16 | 327 | 4.9 | 101.0 | 16 | 604 | 66 | 84 | 9.2 | 37.8 | 2 |
| Jamaal Charles | 1,467 | 2010 |  KC | 16 | 230 | 6.4 | 91.7 | 5 | 468 | 45 | 64 | 10.4 | 29.3 | 3 |
| Michael Turner | 1,371 | 2010 |  ATL | 16 | 334 | 4.1 | 85.7 | 12 | 85 | 12 | 20 | 7.1 | 5.3 | 0 |
 | Chris Johnson | 1,364 | 2010 |  TEN | 16 | 316 | 4.3 | 85.3 | 11 | 245 | 44 | 57 | 5.6 | 15.3 | 1 |
| Maurice Jones-Drew | 1,324 | 2010 |  JAX | 14 | 299 | 4.4 | 94.6 | 5 | 317 | 34 | 44 | 9.3 | 22.6 | 2 |
 | Adrian Peterson | 1,298 | 2010 |  MIN | 15 | 283 | 4.6 | 86.5 | 12 | 341 | 36 | 50 | 9.5 | 22.7 | 1 |
| Rashard Mendenhall | 1,273 | 2010 |  PIT | 16 | 324 | 3.9 | 79.6 | 13 | 167 | 23 | 34 | 7.3 | 10.4 | 0 |
| Steven Jackson | 1,241 | 2010 |  STL | 16 | 330 | 3.8 | 77.6 | 6 | 383 | 46 | 61 | 8.3 | 23.9 | 0 |
| Ahmad Bradshaw | 1,235 | 2010 |  NYG | 16 | 276 | 4.5 | 77.2 | 8 | 314 | 47 | 58 | 6.7 | 19.6 | 0 |
| Ray Rice | 1,220 | 2010 |  BAL | 16 | 307 | 4.0 | 76.3 | 5 | 556 | 63 | 83 | 8.8 | 34.8 | 1 |
| Peyton Hillis | 1,177 | 2010 |  CLE | 16 | 270 | 4.4 | 73.6 | 11 | 477 | 61 | 77 | 7.8 | 29.8 | 2 |
| Darren McFadden | 1,157 | 2010 |  OAK | 13 | 223 | 5.2 | 89.0 | 7 | 507 | 47 | 61 | 10.8 | 39.0 | 3 |
| Cedric Benson | 1,111 | 2010 |  CIN | 16 | 321 | 3.5 | 69.4 | 7 | 178 | 28 | 37 | 6.4 | 11.1 | 1 |
 | LeSean McCoy | 1,080 | 2010 |  PHI | 15 | 207 | 5.2 | 72.0 | 7 | 592 | 78 | 90 | 7.6 | 39.5 | 2 |
 | Matt Forte | 1,069 | 2010 |  CHI | 16 | 237 | 4.5 | 66.8 | 6 | 547 | 51 | 70 | 10.7 | 34.2 | 3 |
| BenJarvus Green-Ellis | 1,008 | 2010 |  NE | 16 | 229 | 4.4 | 63.0 | 13 | 85 | 12 | 16 | 7.1 | 5.3 | 0 |
 | LeGarrette Blount | 1,007 | 2010 |  TB | 13 | 201 | 5.0 | 77.5 | 6 | 14 | 5 | 7 | 2.8 | 1.1 | 0 |
| Fred Jackson | 927 | 2010 |  BUF | 16 | 222 | 4.2 | 57.9 | 5 | 215 | 31 | 54 | 6.9 | 13.4 | 2 |
 | LaDainian Tomlinson | 914 | 2010 |  NYJ | 15 | 219 | 4.2 | 60.9 | 6 | 368 | 52 | 79 | 7.1 | 24.5 | 0 |
| Thomas Jones | 896 | 2010 | KC | 16 | 245 | 3.7 | 56.0 | 6 | 122 | 14 | 20 | 8.7 | 7.6 | 0 |
 | Frank Gore | 853 | 2010 |  SF | 11 | 203 | 4.2 | 77.5 | 3 | 452 | 46 | 72 | 9.8 | 41.1 | 2 |
| Brandon Jacobs | 823 | 2010 | NYG | 16 | 147 | 5.6 | 51.4 | 9 | 59 | 7 | 13 | 8.4 | 3.7 | 0 |
| Felix Jones | 800 | 2010 |  DAL | 16 | 185 | 4.3 | 50.0 | 1 | 450 | 48 | 52 | 9.4 | 28.1 | 1 |
| Knowshon Moreno | 779 | 2010 |  DEN | 13 | 182 | 4.3 | 59.9 | 5 | 372 | 37 | 48 | 10.1 | 28.6 | 3 |
| Jonathan Stewart | 770 | 2010 |  CAR | 14 | 178 | 4.3 | 55.0 | 2 | 103 | 8 | 14 | 12.9 | 7.4 | 1 |
| Shonn Greene | ||||||||||||||
| Ryan Torain | ||||||||||||||
 | Marshawn Lynch | ||||||||||||||
| Tim Hightower | ||||||||||||||
| Mike Tolbert | ||||||||||||||
| Ronnie Brown | ||||||||||||||
| Chris Ivory | ||||||||||||||
| Brandon Jackson | ||||||||||||||
| Ryan Mathews | ||||||||||||||
 | Michael Vick | ||||||||||||||
| Ricky Williams | ||||||||||||||
| Michael Bush | ||||||||||||||
| Jahvid Best | ||||||||||||||
| Danny Woodhead | ||||||||||||||
| Justin Forsett | ||||||||||||||
| Donald Brown | ||||||||||||||
| Joseph Addai | ||||||||||||||
| Rashad Jennings | ||||||||||||||
| Mike Goodson | ||||||||||||||
| Cadillac Williams | ||||||||||||||
| Beanie Wells | ||||||||||||||
| Willis McGahee | ||||||||||||||
| Marion Barber | ||||||||||||||
| Josh Freeman | ||||||||||||||
| DeAngelo Williams |
StatMuse has season-level data for rushing yards going back to the 1932 season.