8 players are tied for the most total touchdowns in a Week-1 game, with 4 touchdowns. The first three are Priest Holmes on September 8, 2002, Emmitt Smith on September 4, 1995 and Thurman Thomas on September 6, 1992.
8 players are tied for the most total touchdowns in a Week-1 game, with 4 touchdowns. The first three are Priest Holmes on September 8, 2002, Emmitt Smith on September 4, 1995 and Thurman Thomas on September 6, 1992.