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Between July 25, 2020 and July 25, 2025, Saquon Barkley has rushed for the most yards by a running back in a game, with 255 yards against the Rams on November 24.

most rushing yards by a running back last 5 years in a game
Interpreted as:
most rushing yards by a running back last 5 years in a regular-season game
11/24/2024Barkley1/3/2021Taylor1/3/2021Henry11/27/2022Jacobs10/30/2022Henry12/22/2024Taylor12/13/2020Henry10/18/2020Henry11/8/2020Cook12/9/2021Cook9/24/2023Achane9/29/2024Henry11/15/2020Jones1/9/2022Penny1/6/2024Taylor1/3/2022Harris11/21/2021Taylor12/26/2020Wilson9/19/2021Henry9/27/2020Cook12/17/2023Cook1/7/2024Hall255253250229219218215212206205203199192190188188185183182181179178
NAMERUSH YDSDATETMOPPATTYPCRUSH TDREC YDSRECTRGAVGREC TD
Saquon BarkleySaquon Barkley25511/24/2024
PHIPHI
@
LARLAR
269.82474411.80
Jonathan TaylorJonathan Taylor2531/3/2021
INDIND
vs
JAXJAX
308.421121.00
Derrick HenryDerrick Henry2501/3/2021
TENTEN
@
HOUHOU
347.420000
Josh JacobsJosh Jacobs22911/27/2022
LVLV
@
SEASEA
336.92746712.30
Derrick HenryDerrick Henry21910/30/2022
TENTEN
@
HOUHOU
326.829119.00
Jonathan TaylorJonathan Taylor21812/22/2024
INDIND
vs
TENTEN
297.530000
Derrick HenryDerrick Henry21512/13/2020
TENTEN
@
JAXJAX
268.327223.50
Derrick HenryDerrick Henry21210/18/2020
TENTEN
vs
HOUHOU
229.62522526.00
Dalvin CookDalvin Cook20611/8/2020
MINMIN
vs
DETDET
229.42462223.00
Dalvin CookDalvin Cook20512/9/2021
MINMIN
vs
PITPIT
277.62171317.00
De'Von AchaneDe'Von Achane2039/24/2023
MIAMIA
vs
DENDEN
1811.3230447.52
Derrick HenryDerrick Henry1999/29/2024
BALBAL
vs
BUFBUF
248.3110333.31
Ronald JonesRonald Jones19211/15/2020
TBTB
@
CARCAR
238.316126.00
Rashaad PennyRashaad Penny1901/9/2022
SEASEA
@
ARIARI
238.310000
Jonathan TaylorJonathan Taylor1881/6/2024
INDIND
vs
HOUHOU
306.318224.00
Najee HarrisNajee Harris1881/3/2022
PITPIT
vs
CLECLE
286.7118336.00
Jonathan TaylorJonathan Taylor18511/21/2021
INDIND
@
BUFBUF
325.8419336.31
Jeff Wilson Jr.Jeff Wilson Jr.18312/26/2020
SFSF
@
ARIARI
228.30211221.01
Derrick HenryDerrick Henry1829/19/2021
TENTEN
@
SEASEA
355.2355669.20
Dalvin CookDalvin Cook1819/27/2020
MINMIN
vs
TENTEN
228.2118259.00
James CookJames Cook17912/17/2023
BUFBUF
vs
DALDAL
257.21422321.01
Breece HallBreece Hall1781/7/2024
NYJNYJ
@
NENE
374.8112226.00
Derrick HenryDerrick Henry17811/29/2020
TENTEN
@
INDIND
276.637243.50
Jonathan TaylorJonathan Taylor1771/5/2025
INDIND
vs
JAXJAX
345.213123.00
Breece HallBreece Hall17710/8/2023
NYJNYJ
@
DENDEN
228.0117335.70
Dameon PierceDameon Pierce
Saquon BarkleySaquon Barkley
D'Andre SwiftD'Andre Swift
Austin EkelerAustin Ekeler
Rhamondre StevensonRhamondre Stevenson
Jonathan TaylorJonathan Taylor
Cam AkersCam Akers
Bijan RobinsonBijan Robinson
Rashaad PennyRashaad Penny
Jonathan TaylorJonathan Taylor
Derrick HenryDerrick Henry
Aaron Jones Sr.Aaron Jones Sr.
Saquon BarkleySaquon Barkley
Kenneth Walker IIIKenneth Walker III
Zack MossZack Moss
D'Onta ForemanD'Onta Foreman
Joe MixonJoe Mixon
Saquon BarkleySaquon Barkley
Kenyan DrakeKenyan Drake
Dalvin CookDalvin Cook
Derrick HenryDerrick Henry
Rhamondre StevensonRhamondre Stevenson
Jonathan TaylorJonathan Taylor
Nick ChubbNick Chubb
Clyde Edwards-HelaireClyde Edwards-Helaire

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