42 players scored 0 interception touchdowns. The first three are Drew Bledsoe on November 13, 1994, Vinny Testaverde on December 24, 2000 and on December 6, 1998 and Patrick Mahomes on November 6, 2022.

most pick sixes thrown in a NFL game by a player
Interpreted as:
most pick sixes thrown in a NFL regular-season game by a player

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