Jesse Palmer has averaged the fewest passing yards per attempt by a quarterback in a game with 40+ passing attempts, with 2.6 yards against the Panthers on December 28, 2003.

fewest passing yards per attempt in a game with 40 or more att by a qb with 3.4 ypa or fewer
Interpreted as:
fewest passing yards per attempt in a regular-season game with 40 or more passing att by a qb with 3.4 ypa or fewer

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