Lou Gehrig has the highest OPS by a first baseman in a season, with an OPS of 1.240 in 1927.

what first baseman has the highest ops in a season between 50 and 125 at bats
Interpreted as:
What first baseman has the highest ops with a minimum of 3.1 PA per team game in a season between 50 and 125 at bats?

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