8 players are tied for the most strikeouts in a game with 4+ plate appearances, with 6 strikeouts. The first three are Geoff Jenkins on June 8, 2004, Alex Gonzalez on September 9, 1998 and Sam Horn on July 17, 1991.
8 players are tied for the most strikeouts in a game with 4+ plate appearances, with 6 strikeouts. The first three are Geoff Jenkins on June 8, 2004, Alex Gonzalez on September 9, 1998 and Sam Horn on July 17, 1991.