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Babe Ruth had the most games with 2+ hits with 1+ home run, with 409 games.

most career games with 2 or more h and 1 or more hr by a batter
Interpreted as:
most career regular-season games with 2 or more h and 1 or more hr by a batter
RuthAaronRodriguezBondsPujolsMaysSosaRamirezRobinsonGriffeyCabreraFoxxOrtizThomeMusialGehrigPalmeiroSheffieldOttGuerreroMantleJones409407381379369362332326322314311304300297294293290283282281276275
NAMEGHHRABR2B3BRBIBBHBPSOSBCSPATBXBHSHSFIBBGIDPAVGOBPSLGOPS
Babe RuthBabe Ruth4099694831,626775117311,0343044152211,9472,59763113.596.6601.5972.257
Hank AaronHank Aaron4079714701,7126841021293114021333181,8652,5075840113427.567.5971.4642.061
Alex RodriguezAlex Rodriguez3819274481,6276939579091492121858121,8132,3805502141224.570.6061.4632.069
Barry BondsBarry Bonds3798834541,46367811217860261713974241,7402,391583097418.604.6611.6342.296
Albert PujolsAlbert Pujols3698814381,5506371123878134151251591,7102,3135530114135.568.6021.4922.095
Willie MaysWillie Mays3628764291,5216418216775133410263211,6712,2775270131215.576.6061.4972.103
Sammy SosaSammy Sosa3327804071,3975568410801119120428231,5242,105501072516.558.5911.5072.097
Manny RamirezManny Ramirez3267633821,32955510858231498192771,5012,0274951142623.574.6131.5252.139
Frank RobinsonFrank Robinson3227603771,3185728116732136171202591,4802,004474362621.577.6181.5202.139
Ken Griffey Jr.Ken Griffey Jr.3147493711,328532101473613391442781,4811,9714760113615.564.6021.4842.086
Miguel CabreraMiguel Cabrera3117743561,29052011027331204146361,4251,9564680113422.600.6301.5162.146
Jimmie FoxxJimmie Foxx3047353611,24555689217921780114101,4291,94947165.590.6421.5652.207
David OrtizDavid Ortiz3007033511,23547210446791263138101,3701,868459063024.569.6071.5132.120
Jim ThomeJim Thome2976833471,15851810456651763210131,3411,838456042311.590.6431.5872.230
Stan MusialStan Musial2947263331,2375148317676145556431,3941,84243316918.587.6291.4892.118
Lou GehrigLou Gehrig2937503411,22956610032809170559191,4121,9374738.610.6591.5762.235
Rafael PalmeiroRafael Palmeiro2906913241,21345680966110971091441,3411,761413012919.570.6021.4522.054
Gary SheffieldGary Sheffield2836693211,14947477466014098133151,3091,717402291711.582.6261.4942.120
Mel OttMel Ott2826533321,13950767969515355771,2991,73440820.573.6251.5222.148
Vladimir GuerreroVladimir Guerrero2816703231,1724527666287412953191,2671,727405092524.572.5971.4742.070
Mickey MantleMickey Mantle2766493231,100486581163016821292951,2731,698392031713.590.6431.5442.187
Chipper JonesChipper Jones2756583161,149479831260912311122551,2801,713411072016.573.6111.4912.102
Reggie JacksonReggie Jackson2756423191,120437867642115717128121,2461,699412131112.573.6141.5172.131
Dave WinfieldDave Winfield2746573051,1714406076209441162981,2751,646372242423.561.5931.4061.999
Ernie BanksErnie Banks2736423191,1454445914651751082571,2411,6863920112023.561.5861.4722.058
Ted WilliamsTed Williams
Frank ThomasFrank Thomas
Eddie MurrayEddie Murray
Adrian BeltreAdrian Beltre
Mike SchmidtMike Schmidt
Carl YastrzemskiCarl Yastrzemski
Willie StargellWillie Stargell
Mark McGwireMark McGwire
Harmon KillebrewHarmon Killebrew
Carlos BeltranCarlos Beltran
Mike PiazzaMike Piazza
Jeff BagwellJeff Bagwell
Fred McGriffFred McGriff
Andre DawsonAndre Dawson
Willie McCoveyWillie McCovey
Carlos DelgadoCarlos Delgado
Billy WilliamsBilly Williams
Eddie MathewsEddie Mathews
Juan GonzalezJuan Gonzalez
Cal Ripken Jr.Cal Ripken Jr.
Jose CansecoJose Canseco
Tony PerezTony Perez
Jim RiceJim Rice
Paul KonerkoPaul Konerko
Harold BainesHarold Baines
StatMuse has game-level data for games going back to the 1908 season.
Some of the information used here was obtained free of charge from Retrosheet.

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